ALK inhibitor 2 ( ALK inhibitor 2; MDK-8384; MDK 8384 )

产品货号. M19086 CAS No. 761438-38-4

COA

Datasheet

HNMR

HPLC

MSDS

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产品名称

ALK inhibitor 2
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
产品描述

MDK-8384, also known as ALK inhibitor 2, is a potent and selective ALK inhibitor. MDK-8384 has CAS#761438-38-4. MDK-8384 was reported in J Med Chem. 2013;56(14):5675-90.
同义词

ALK inhibitor 2; MDK-8384; MDK 8384
通路

Others
靶点

Other Targets
受体

ALK
研究领域

Cancer
适应症

——

CAS Number

761438-38-4
分子量

518.03
分子式

C23H28ClN7O3S
纯度

98%
溶解度

DMSO : 50 mg/mL 96.52 mM;H2O : < 0.1 mg/mL
SMILES

c1cc(c(cc1)Nc1c(cnc(n1)Nc1c(cc(cc1)N1CCN(CC1)C)OC)Cl)S(=O)(=O)NC
化学全称

2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

1. A Dose Finding Study With Oral LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase (ALK).

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