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ALK inhibitor 2

CAS No. 761438-38-4

ALK inhibitor 2 ( ALK inhibitor 2; MDK-8384; MDK 8384 )

产品货号. M19086 CAS No. 761438-38-4

ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1345 有现货
5MG ¥2049 有现货
10MG ¥2876 有现货
25MG ¥4771 有现货
50MG ¥6820 有现货
100MG ¥9153 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    ALK inhibitor 2
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.
  • 产品描述
    MDK-8384, also known as ALK inhibitor 2, is a potent and selective ALK inhibitor. MDK-8384 has CAS#761438-38-4. MDK-8384 was reported in J Med Chem. 2013;56(14):5675-90.
  • 同义词
    ALK inhibitor 2; MDK-8384; MDK 8384
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ALK
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    761438-38-4
  • 分子量
    518.03
  • 分子式
    C23H28ClN7O3S
  • 纯度
    98%
  • 溶解度
    DMSO : 50 mg/mL 96.52 mM;H2O : < 0.1 mg/mL
  • SMILES
    c1cc(c(cc1)Nc1c(cnc(n1)Nc1c(cc(cc1)N1CCN(CC1)C)OC)Cl)S(=O)(=O)NC
  • 化学全称
    2-[[5-chloro-2-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]-N-methylbenzenesulfonamide

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. A Dose Finding Study With Oral LDK378 in Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase (ALK).
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